Submissions to the EMA and the national medicines boards in Europe are mainly text-based, containing aggregate-level results of clinical trials based on the applicant's statistical analysis.
Moreover, data from clinical trials based on the hypothesis suggest that it has real value for patients.
Several clinical trials based on the use of MSC are currently underway for therapeutic purposes.
Established methods for comparing drug effects [9] include designing randomized clinical trials based on the null hypothesis.
Principal components analysis was employed to investigate any underlying relationship among the different trials based on the agronomic and quality parameters of radish plants at harvest.
Ethyl ester prodrug 42 advanced to human clinical trials based on the excellent intestinal fluid stability, good permeability and superior efficacy in non-human primates.
They were changed to ϕ = 1.5 and ζ = 0.15 for the two later trials, based on the R-test result for the 2008 probabilities calculated by LN-Bayes and by LN-SST.
After the biostatisticians contacted the Duke scientists and the journals that published their work, Duke launched trials based on the technology, using it to assign patients to different treatments.
Corresponding simulations of the machining processes of these cutting trials based on the machining dynamics model are investigated and the simulation results are analysed and compared to the measurements.
In this respect, new fundamental insights into the biological mechanisms displayed by Ins, as well as clinical trials based on the myoIns + D-chiroIns formulations, have already provided encouraging results.
Three trials based on the ontogenetic theory of local tumour spread using total mesometrial resection (TMMR) extended mesometrial resection (EMMR) and laterally extended endopelvic resection (LEER) for the treatment of cervix cancer, included a total of 367 patients stages I-B to II-B.
