Suggestions(1)
Exact(14)
The choice of the first DMARD has been the topic of many trials and guidelines.
4 Clinical trials and guidelines are described in Additional file 1.
9 The definition of intensive glycaemic control varies among trials and guidelines.
In surgical ICU patients, and especially in CTS patients, there are trials and guidelines evaluating preventive measures [ 46, 47].
Many persons at low risk for cardiovascular events also take low-dose aspirin in response to the positive publicity surrounding the prevention trials and guidelines [ 18].
European routine clinical practice was influenced by landmark trials and guidelines which impacted on the implantation of cardiac resynchronization therapy in over 25% of such patients.
Similar(45)
Evidence from randomised trials and guideline recommendations all support the use of different strategies according to risk status.
Other papers describing barriers made some similar suggestions, for example, accounting for the patient's context, 10 30 31 33 focusing on generic instead of disease-specific outcomes, 34 35 providing guidance in prioritising guideline recommendations 16 17 32 and improving the external validity of clinical trials and guideline recommendations.
Randomized controlled trials, reviews, and guidelines evaluating the impact of age on overall survival and/or toxicity with adjuvant and palliative therapies for colorectal adenocarcinoma were selected.
Recent landmark randomized trials and society guidelines have significantly revised the management of carotid artery disease.
Further, this gap in knowledge hinders planning for clinical trials and therapeutic guidelines.
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