Suppose that the numbers of patients in the two groups are the same (majority of clinical trials allocate (approximately) the same number of patients in two contrast groups) and we denote this number as n.
There was some evidence to suggest that the further the trial deviates from routine clinical practice the more likely the application is to describe PPI, and PPI was particularly frequent in applications for blinded trials or trials allocating participants to placebo only.
When a trial allocated participants to more than one intervention, we abstracted data from the arm allocated to receive antibiotics.
56 57 58 When a trial allocated participants to more than one antibiotic arm, we combined the data from both arms to avoid unit of analysis errors.
This model was compared with a Standard care model, which in accordance with clinical practice in Sweden at the onset of the trial allocated equal time to preparation for childbirth and parenthood.
Of these, one trial allocated patients to higher (2.5 L/h) or lower (1 L/h) dose continuous veno-venous hemofiltration (CVVH) or continuous veno-venous hemodialysis (CVVHD) in a 2 × 2 factorial design [ 24].
It will be a randomised controlled trial, allocating the participants into two groups to compare their progress.
This trial allocates eligible participants at random between MBCT and TAU, CPE and TAU, and TAU alone in a ratio of 2 2 1, stratified by presence of suicidal ideation or behaviour and current anti-depressant use.
