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These are just some of the fledgling wellbeing trends we're likely to see charities trialling over the coming years.
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After successful pre-clinical in vivo combination studies it entered clinical trial; over 20 trials have now been reported.
A cerebellar circuit model that reproduces the features of trial-over-trial depression of simple-spike firing rate and trial-over-trial learning in eye velocity.
Finally, trial-over-trial learning in eye velocity is closely aligned to the trial-over-trial changes in simple-spike firing rate for the 4 pairs of trials, supporting a causal link between trial-over-trial depression in neural firing and trial-over-trial learning in behavior.
The pink shading shows the analysis interval for trial-over-trial learning.
The arrowhead on the horizontal velocity records points out trial-over-trial learning.
(A and D ) Trial-over-trial change in simple-spike firing rate and eye velocity.
Subsequently, the authors show their data on single trial and trial-over-trial learning as observed in vivo.
10.7554/eLife.01574.006 Figure 4. Mechanisms of CS-linked trial-over-trial depression of simple-spike firing rate and same-trial facilitation.
We attribute this component of trial-over-trial-depression to CS-linked plasticity that occurs during trial-over-trial behavioral learning, because it persists after we control for same-trial facilitation.
CS-linked trial-over-trial depression of simple-spike firing was demonstrated before (Medina and Lisberger, 2008), and we have verified here that trial-over-trial depression results partly from single-trial plasticity.
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