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In New York - and, actually, Camden did this too - the city planners trialled proposed new cycle routes with temporary planters, to check traffic flow, before making a final decision and then fully segregating the lines.
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We suggest that in the design phase of clinical trials, proposed eligibility criteria be scrutinized closely.
Nonetheless, all clinical trials proposed to establish effectiveness must incorporate common elements in order for the appropriate legal and scientific standards of drug approval to be met.
"The further trials proposed by the committee are a reflection of the fact we want to make sure that the pink ball is sufficiently durable to stand up to the rigours of first-class cricket".
The three-stage optimal design for phase II clinical trials proposed by Ensign et al. [29] was used in each subgroup (group A: previously untreated, group B: previously treated with chemotherapy).
This design was similar to the "cohort multiple randomized controlled trial," proposed elsewhere.
Plaintiff, at time of trial, proposed to enter both cases neither party; settled.
Multistage designs for phase II clinical trials proposed by Gehan, Fleming, Simon and Ensign are described and compared.
The trial proposed here is an original study in which, for the first time, antibiotics are compared with placebo after LC in cases of ACC.
This is the only current randomised adjuvant trial proposed that uses the 3-weekly schedule and is also testing two durations of herceptin.
The trial proposed is sufficiently powered and, to the best of our knowledge, the first to allow conclusions on the effect of RADTs in adults with pharyngitis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com