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Design: This study was a clinical, prospective, open, repeated measures trial, with data collection between January and July 2015.
In a statement from the International Society for Stem Cell Research ISSCRR), Yamanaka bemoaned the Italian decision, stating that "stem cell therapy and treatment decisions should not be made outside of a controlled clinical trial with data on safety and efficacy"[33].
This one year study was conducted as a cluster randomized single-blinded controlled trial, with data undergoing an intention-to-treat analysis (ITT).
Therefore, this leaves 27 missing journal articles, in 10 separate reviews that contain at least one trial with data not found by the BRSS.
The Prevention of Pelvic Infection study is the only trial with data about the baseline prevalence of chlamydia in the control group, which allowed us to investigate the incidence of PID amongst untreated women.
The design was a two-group randomized-controlled trial with data collected at baseline (time 1) then after the intervention at one month (time 2) and 3 months (time 3) postbaseline.
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The pull factors are cost-effective trials, with data transfer to developed countries being legitimized by the World Trade Organization ( WTO), patient numbers, disease profile, and availability of highly adaptable internationally trained investigators who have no language barriers.
Published in the journal Family Practice in September 2012, the team's analysis combines data from the eight unpublished trials with data from three published ones and gives a far less obstructed view of Tamiflu's effects.
Trials with data missing for more than 5 s were discarded in order to avoid unwanted influences (e.g. closed eyes).
When comparing imaging data from simple singing trials with data from voice perception trials prior to auditory training, the experimental group recruited a network comprised of auditory cortical regions, sensorimotor cortex, premotor areas, insulae, thalamus, basal ganglia, and cerebellum (Table S1), which is similar to the functional network that we and others previously reported [16] [18].
We analysed data from the first period in crossover trials with data from parallel trials.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com