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More than a hundred demonstrators gathered downtown to march against the verdict in the George Zimmerman trial, which allowed a man who shot and killed an unarmed black teenager to walk free.
An additional two participants showed sudden head motion only in the first trial, which allowed the use of the imaging data obtained from these two participants after the first trial was removed.
By contrast, in the Amado trial, which allowed crossover, this occurred in 90/119 KRAS WT patients resulting in no OS benefit being demonstrated.
A possible limitation is the short-term length of the trial, which allowed for detection of early rapid improvements in PROs but excluded analysis of longer-term outcomes.
In most cases, data were collected before and after the trial, which allowed investigation of the comparability of participants at baseline.
To inform how consent is sought for future paediatric critical care trials, we explored the views and experiences of parents and practitioners involved in the CATheter infections in CHildren (CATCH) trial, which allowed for deferred consent in certain circumstances.
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Yet the records of her trial, which allow her to speak in her own voice, were accessible, as were those of the second trial, which rehabilitated her character and quashed the accusations that led to her execution.
One approach is a cluster-randomised trial, which allows assessment of herd protection in a way that minimises biases.
Illustrated is the use of a patient enrichment adaptive design in a randomized phase II trial which allows the evaluation of treatment benefits by the biomarker expression level and makes interim adjustment according to the pre-specified rules.
In the recognition task, basic emotional expressions were morphed between their full expression and neutral in 2% steps, and presented as dynamic video-clips with final frames of different emotional intensity for each trial, which allows for a fine-grained measurement of emotion sensitivity.
We determined the association between these polymorphisms and tamoxifen sensitivity in the context of a randomized trial, which allows for the discernment of prognosis from prediction.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com