Exact(11)
Further withdrawal from treatment and dropout from the trial were calculated.
Both incremental ratios over time and the maximal incremental ratios from each trial were calculated.
The costs of this trial were calculated only for the study period (12 months) and therefore no adjustments were required for future discounting.
The boundaries for the sequential trial were calculated on the primary outcomes of a difference of cervical dilatation ≥1 millimetre, with the assumption of a type 1 error of 0.05 and a power of 0.95.
Mean (SE) utilities at baseline of the UPLIFT trial were calculated to be 0.809 0.0088) in patients with moderate disease, 0.762 (0.009) in patients with severe disease and 0.655 (0.024) in patients with very severe disease.
Sample size estimates for the main trial were calculated to be 370 per group, based on an effect size (difference between groups divided by the pooled SD) of 0.23, assuming a two-sided α = 0.05 and β = 0.2.
Similar(49)
Probe trial is calculated as percent time spent in target quadrant.
Here, the semantic coordinate of each trial was calculated as the sum of semantic coordinates of All available features of the implied target object.
That is, the semantic coordinate of each trial was calculated as the sum of semantic coordinates of All available features of the implied target object (see model 4 above).
A sample size for this pilot trial was calculated according to the method proposed by Whitehead et al. [16].
Based on these parameters, the improvement during each phase of the trial compared to the state of the ABG before the trial is calculated in percent.
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