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For each trial, we took the absolute distance of error from the target.
In considering causality in the absence of a randomised controlled trial, we took into account confounding by risk modifying factors and the temporality of cause and effect.
Whilst the ideal situation would be to test its psychometric properties for this different population before using it in a trial; we took the pragmatic decision to validate it concurrently with the phase II trial.
For each trial, we took the portion of the data from 300 ms before maze onset to 200 ms before movement onset, and applied GPFA with a 20 ms bin width and 12 dimensions.
With this trial, we took the first steps to clinically develop the multi-antigen approach, combining the DNA encoding five pre-erythrocytic stage antigens into a plasmid mixture (MuStDO5) and assessing intramuscular administration via jet injection in 32 (dropping to 31) healthy, malaria-naïve adults, aiming to induce cell-mediated protection.
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In a criminal trial, we take a complicated narrative of cause and effect and match it to a simple, impersonal code: first-degree murder, or second-degree murder, or manslaughter.
For each trial, we take the first 30 iterations (20 for BCell lymphoma) to identify the pathways represented by the selected genes using queries to the Gene Ontology.
Five months after its application in field trials, we took soil samples for reisolating FZB42 derivatives.
If reductions in both systolic and diastolic blood pressures were reported (as in most trials), we took the average of the two risk estimates (more strongly predictive than either alone 25).
As mortality from breast cancer in 1985 was higher in England than in those trials, we took as baseline the rate for England for 1985, before screening was introduced.
For a given combination tested in multiple trials, we take into account that p may be different due to the use of different dose, schedule or cancer subtype on each trial.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com