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Using an event-related design, we modeled three components of the match-to-sample trial: visual encoding, delay, and discrimination.
During each training trial, visual probes always appear in the location of the neutral pictures.
In the INITIATIVE trial, visual symptoms were reported by 16.3% of patients receiving ivabradine 7.5 mg twice daily and 5.6% of those in the atenolol 100 mg once daily group (Tardif et al. 2005).
In a placebo-controlled trial, visual symptoms were reported by 14.8% of patients receiving ivabradine 10 mg twice daily during the double-blind phase, versus 0% in the placebo group (Borer et al. 2003).
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We used this system to record spatial properties of cat brain activity in vivo, including sleep spindles, single-trial visual evoked responses and electrographic seizures.
In the practice trials visual feedback was presented.
In the training session, the participants were asked to discriminate between static and moving visual stimuli for 80 trials: visual stimuli (2: static/moving) × eccentricities (4) × repetitions (10).
In a learning phase preceding the non painful and painful trials, visual and verbal feedbacks were provided.
Additionally, over the first 20 practice trials, visual feedback regarding lever position was faded (i.e., linearly reduced).
Additionally, over the first 20 practice trials, visual feedback that had been provided to aid participants' initial understanding of the task was faded [ 14].
Before testing, participants were familiarized with the experimental procedures, including practice trials; visual aids were used where possible, to ensure the participant understood the task (Supplementary Fig. 1 and Supplementary material).
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