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Prosecutors here noted that she is also in the vanguard of a growing trial trend: in Arizona, Hawaii, Idaho, Indiana and some other states in the last few years, courts have allowed such trained dogs to offer children and other vulnerable witnesses nuzzling solace in front of juries.
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Although only the EORTC trial showed a significant survival advantage for CRT, the RTOG trial trended in the same direction and showed a significant increase in progression-free survival.
The α-level for significance was 0.05; however, as this was a pilot investigation being used to determine outcomes of interest for a larger parent trial, trends are also reported with an α-level of p < 0.1.
In a retrospective analysis of the moderately severe to severely ill patient subset from this trial the trend toward improved global response persisted [ 39].
In the Memory in Diabetes study of the Action to Control Cardiovascular Risk in Diabetes (ACCORD-MIND) trial, a trend was observed for decelerated cognitive decline in the treatment arm that was subjected to intensified glucose-lowering treatment [ 31].
In the HIACE trial, a trend toward reduction in the frequency of hospital admissions for COPD (0.5 times/year vs 0.80 times/year) and average number of hospitalization days (1.8 days/year vs 4.2 days/year) was observed with NAC 600 mg b.i.d. as compared with placebo (60).
The proportion of surgical trials in 2006 was higher than in 2000, whereas the proportion of drugs trials decreased a trend that has also been reported elsewhere.
Nielson said rap music is increasingly being used as evidence in trials, a trend reflective of systemic racial oppression in the US.
"From everything we're seeing in the clinical trials, the trend is that the statins are being shown to be helpful in many more situations," said Dr. Dana McGlothlin, a cardiologist at the University of California, San Francisco Medical Center.
Exenatide demonstrated no significant effect on HR or BP in this 12-week trial, although trends toward decreased SBP were observed.
15 These developments have led to a rapid increase in their use in clinical trials, a trend which is likely to continue.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com