For several trials, this information is not provided in the published aggregate data.
For retrieval trials, this information was not orthogonal in our experiment (a specific color appeared always on the left).
"To say that Schwarz would very likely have been acquitted at the first trial had this information been disclosed to Schwarz's then-counsel is no rhetorical excess," the defense lawyers said.
If this data is treated as a field trial, then this information can be used to more adequately target the items to the cohort for a main study.
Furthermore, in the clinical trial setting, this information is equally important to determine if there is sufficient evidence to support a new treatment modality.
In addition, we had to make several assumptions about the methodology used in the TEMSO trial, because this information was not available at the time of planning the analysis.
This evaluation was also unable to consider the impact of variation in cost within each type of prostheses (ie, within the three types of THA, or beyond the single RSA used in the trial) as this information is not generally available.
Although the study by Ferrajoli et al. proposes novel biomarkers for CLL, the clinical utility of these findings is questionable as 30 50% of patients never require therapy at all, and therefore, outside of a clinical trial context, this information is unlikely to result in changes to patient management.
The US, Norway, and UK trials provided this information through mortality curves.
There were four trials with this information for artemisinin-based partners: Shekalaghe 2007, Smithuis 2010 (five comparisons), Sutanto 2013, and Vasquez 2009.
