Cases of malaria identified on the basis of reported fever alone should not be included in the primary endpoint of a clinical trial since the specificity of the endpoint is low.
This is consistent with the findings from a Dutch screening trial, where the specificity of DRE was 91% (Schröder et al, 1998).
For disease perception, there was a larger effect for patients in the angina trials, possibly reflecting the specificity of the scale for angina/concern about having a heart attack, which may be less relevant for healthier CECaT patients, for example.
The objective of this trial is to investigate the specificity of procedural practice in laparoscopic simulator training.
The objective of this trial is to examine the specificity of proficiency-based procedural simulator training and to examine transferability between two different procedural modules.
34 In this trial the lower specificity of the MoleMate system resulted in an increased volume of referrals, but the detection rates of melanoma in both arms were high.
Few ICU databases or clinical trials record cause-specific mortality and so the specificity of the relationship is currently unclear.
The specificity of PSA screening in the Finnish screening trial is acceptable.
Trials with new nets aim to reduce bycatch, or improve the specificity of fleets for certain fish species or ages - but again, fish die in the process.
However, the specificity of the product makes the drug development process, including clinical trials, a considerable challenge.
