The effect of trial and the interaction between group and trial were not significant, both Fs (1, 78) < 1.
On the one hand, it was designed as a 2 × 2 factorial trial and the interaction between the two treatment factors was unclear; on the other hand, in the trial [23], the clinicians used a 50% decrease from previous value as a stopping rule, which was lower than that of other studies.
Finally, with uncertainty in clinical endpoints and trial design, the interaction between a wide range of stakeholders is extremely important to explore ways to optimize development pathways.
We checked this assumption by tests of heterogeneity across trials, testing the interaction between type of bandage and trial.
Further randomised trials evaluating the interaction between digoxin and sex have not emerged.
The important point is that for both animals, psychometric functions were steeper (performance improved) in large reward trials, and the interaction between reward and microstimulation shift was highly significant for each animal separately whether considered site-by-site or in the data pooled across sites.
To support this hypothesis of co-acting top-down mechanisms, we performed a trial-by-trial analysis investigating the interaction between reward-induced motivation and top-down cognitive control.
Model effects included treatment (MEL, CON), trial day, and the interaction between these two variables.
Based on conflicting data from observational studies and randomized trials [ 6- 8], the interaction between maternal risk and level of prenatal care was also included in the logistic regression model.
The interaction between trial arm and time (trial arm×time) was also estimated to determine whether the trial arm had differential effects at short term and long term.
