The left-hand panel of Figure 3 shows the mean percentages of time spent by the two groups in the four corners of the square arena during the test trial after the completion of passive training.
Subjects completed two trials: the first was a practice trial and the completion time for the second trial was recorded.
The recent removal of refecoxib (a cyclo-oxygenase II inhibitor), a drug involved in a large prostate cancer chemoprevention trial, and the completion of recruitment for the SELECT cancer chemoprevention trial utilizing selenium and vitamin E should lead researchers to ponder a similar question in cancer chemoprevention.
The slow rate of accrual in the trial prevented the completion of the planned patients' enrolment within a reasonable time.
Though, the slow accrual rate in the trial prevented the completion of the planned patients' enrolment within a reasonable time.
Once initiated, the second supplement will be continued until the end of the trial or the completion of pregnancy, whichever is the soonest.
21 The protocol should clearly define the end of a trial, usually the completion of recruitment and the appropriate follow-up period.
Previous trials investigating the role of NACT in cervical cancer have used a variety of different drugs with different schedules and a gap of up to 28 days in some trials between the completion of chemotherapy and the start of definitive radiotherapy.
This problem may be more apparent than real since data from three "real world" clinics indicate that the outcome of patients who complete CBT-E, or a CBT-E-like treatment, is similar to that obtained in the main randomised controlled trials although the completion rates are lower (Byrne et al., 2011; Knott, Woodward, Hoefkens, & Limbert, 2014; Turner, Marshall, Stopa, & Waller, 2015).
The aim of prospective registration of clinical trials is to create transparency about the research methodology, and allow access to the trial protocol before the completion of the trial.
