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As patients in this data set were selected for the EGF20001 trial, the applicability of this new prognostic model in the wider non-trial population remains unknown.
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Concerns centre on the widespread implementation of this drug in the treatment of severe sepsis, based upon a single industry-sponsored trial and the applicability of this trial to 'real' patient populations.
An experimental field trial demonstrates the applicability of the developed method for successful use by practitioners in the industry.
Since a case reason can affect corresponding strategies in a trial and the applicability of laws, case reason is always importantly described as "pulling one hair may move the whole body" (Ding 2014).
However, due to volunteer effects and to the unique environment of a randomized controlled trial setting, the applicability of these findings to a real world setting remains uncertain.
Many trials of recruitment methods involve hypothetical trials, and the applicability of their results to the real world is still unknown.
South Asians and ethnic minorities are under-represented in clinical trials, affecting the applicability of results.
This trial will explore the applicability of a new frontier of tele-medicine in infants.
The multinational nature of the ATHENA trial may also impact the applicability of some of the results of this trial to the US population.
The objectives were to: (1) Design Intervention Modelling Experiments by backward engineering a 'real-world' randomised controlled trial (NEXUS); (2) examine the applicability of psychological theories to clinical decision-making; (3) explore whether psychological theories can illuminate how interventions achieve their effects.
It may also cause some concern among clinicians who perceive their practice to be considerably different to that delivered in the 'usual care' arm of the trial and, therefore, question the applicability of the findings to their patients.
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