Exact(11)
The sequential multiple assignment randomized trial (SMART) is particularly useful in developing adaptive treatment strategies.
Sequential multiple randomization trial (SMART) designs are experimental designs used to identify treatment strategies that maximize targeted health outcomes.
The second is the Sequential Multiple Assignment Randomized Trial (SMART), which is an innovative research design especially suited for building time-varying adaptive interventions.
Because subjects in RAD are potentially randomized multiple times with randomizations occurring at crucial points of the disease process, RAD is an example of a Sequential Multiple Assignment Randomized Trial (SMART) (Lavori and Dawson 2004; Murphy 2003).
This paper describes how a sequential, multiple assignment, randomized trial (SMART) design has advantages over a fixed-intervention approach when it comes to collecting data needed to answer both questions.
A sequential multiple assignment randomized trial (SMART) is a novel trial design that can test these dynamic treatment regimens and lead to treatment guidelines that more closely mimic practice.
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Sequential Multiple Assignment Randomized Trials (SMART), use experimental design principles to answer questions for building adaptive interventions including whether, how, or when to alter treatment intensity, type, or delivery.
Sequential, multiple assignments, randomized trials (SMART) can be used to test the decision rules for an adaptive intervention [ 105].
Evidence of mortality reduction has come from a number of meta-analyses of trials (Smart et al, 1995; Hendrick et al, 1997; Kerlikowske, 1997; Moss et al, 2006).
Also, inconclusive long-term results were reported with device-based methods algorithm such as QuickOpt™ (FREEDOM trial) and Smart Delay™ (SMART-AV trial).
In the 1990's, the card companies experimented with various electronic cash systems, notably in a high-profile trial of smart cards in 1997 on the Upper West Side of Manhattan.
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