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However, due to the small numbers of women in the trial, small differences in outcome may not be apparent.
In a placebo-controlled trial, Small et al [ 82] studied the effects of suramin plus hydrocortisone to hydrocortisone alone in men with HRPC and pain requiring opioid analgesics.
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IMPLICATIONS: In this prospective trial, small-dose ropivacaine with fentanyl was as effective as small-dose lidocaine with fentanyl for anorectal procedures in the ambulatory setting.
Error rates for the following scenarios: equally sized trials; one small trial, 1/10th of other trials; 50 50% small and large trials (ratio 1 10); one large trial (10 times larger than other trials).
Phase 1 trials, small tests of its safety in humans, are to start late this year.
It has supported early research and clinical trials, small biotech firms and the biggest of Big Pharma companies, Pfizer.
Limitation:Heterogeneity of device type and antithrombotic therapy across trials, small numbers for some outcomes, and heterogeneous and inconclusive AF results.
Not only were the trials small — limiting how much researchers can learn from each one — but many were low quality as well, the researchers noted.
In clinical practice and clinical trials, small molecules targeting receptor tyrosine kinases or components in the MAPK cascade are used for treatment.
In clinical practice and clinical trials, small molecules targeting RTKs or components in the MAPK cascade are used to treat cancer [1, 3, 4].
The current recommendations for GI decontamination of the poisoned patient are based on a few clinical trials, small case series, retrospective analysis and animal data.
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