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Salvage treatment options for CRPC include enrollment in a clinical trial, secondary hormonal therapy (abiraterone acetate and enzalutamide), immunotherapy (sipuleucel-T), and chemotherapy (docetaxel and cabazitaxel) [ 4].
Statistical analysis of the REFORM trial secondary outcomes Statistical analysis of the REFORM trial secondary outcomes The proportion of fallers versus non-fallers in each group will be compared by logistic regression adjusting for gender, age, centre and history of falling.
Daily assessments included patient-reported outcomes (described in Trial Secondary End Points), serious adverse events, clinical response, clinician statement of reason for continued hospitalization (if applicable), and study drug dose.
As this approach moves from smaller scale efforts into biomarker discovery efforts in clinical trials, rapid and reliable quality assurance approaches are necessary, both from the perspective of ensuring accurate data for inclusion as clinical trial secondary endpoints, and as a measure to contain costs (Group, 2004).
Analysis of 52-week outcomes for BLISS trial secondary endpoints in this subgroup showed that belimumab treatment reduced the risk of a first severe flare, increased the proportion of patients with corticosteroid dose reductions, and decreased the proportion with corticosteroid dose increases, and improved HRQoL.
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Pierre first obtained food using an extracted tool on his seventh experimental trial (Secondary-Any), Corbeau on his fourth (Secondary-Any) and Uék on her fifth (Secondary-Long).
However, in these trials, secondary analysis suggested that intervention using face masks could have a significant effectiveness if implemented rapidly from illness onset or providing a good adherence to the intervention [7].
Examiner 3's passive between-trial secondary rotations were less than 1° for control subjects and slightly more than 1° for the experimental subjects (Tables 3 and 4).
We excluded protocols of randomised trials, secondary analyses, systematic reviews, methodological studies, pilot studies, and early phase trials (for example, phase 1).
We performed primary analyses in all trials; secondary analyses were restricted to contemporary trials with start of patient enrolment in 1999 or later, which corresponds to the start of patient enrolment in COURAGE.
Defendants involved the Land and Housing Bureaus at the municipal and district levels as well as the Municipal Government; in the subsequent appeal process defendants also involved courts of preliminary trials and secondary trials (based on field interviews on Nov. 11, 2005 and Nov. 24, 2005).
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