Neither Pettitte nor Clemens, who was in court Tuesday for a hearing about his trial, responded to interview requests made through their lawyers.
In the study conducted by Faivre et al., 12 of the 35 patients (34.2%) enrolled in the trial responded to the therapy, including two platinum-resistant patients.
The trial responded to a number of criticisms of sleep interventions [ 13] by offering a small group format, a relatively brief intervention, a combination of objective and subjective sleep measures, and a standardized definition of a behavioral sleep problem [ 19].
On average, accuracy [percentage of correctly identified trials (responding to targets and non-responding to fillers)] during the task was high (above 80%).
We explored how investigators of ongoing or planned trials respond to the publication of a trial stopped early for benefit addressing a similar question.
To assess response latencies, the effects of group, sex, and delay block on latency to initiate trials, respond to levers once presented, and collect the reward were analyzed.
In fact, only a small percentage of cancer patients in Phase 1 clinical trials respond to therapies as predicted (Roberts et al., 2004).
As numbers of trials responded to were quite low for some groups in later delay blocks, pairwise correlations were used to investigate the relationship between total number of responses and percentage of responses for the large reward (Lever B).
To assess motivation and participation in the task phase, we set up models to analyze the effect of group, sex, and delay block on total number of trials initiated (nosepoke into food tray to initiate trial and presentation of levers) and total number of trials responded to (choosing a lever once presented).
These trials respond to the realisation of high and growing HIV incidence among women, particularly in developing countries [ 13], and that existing prevention strategies, such as condom use and partner reduction, are not feasible for many women, whose risk may derive mainly from male partner behaviour [ 14, 15].
