I knew people who had entered clinical research some years previously and they had done very well, climbing the ladder toward managing trials reasonably quickly.
They maintain that his original trial lawyer reasonably decided not to get the more primitive DNA tests that were available in 1994.
But as the Court of Appeal observed, the trial court reasonably relied on the District's expert testimony that any attempt to "quick fix" the problem by realigning the diversion levee and lining it with stronger material would have failed during Tropical Storm Dolores.
This brief overview of the overarching arguments in the debate demonstrates that proponents and critics alike are predominantly focused on determining whether the SUPPORT trial presented "reasonably foreseeable risks" to enrolled infants, pursuant to a section of U.S. regulation on human participants research, known as the Common Rule (45 CFR 46.116(a)(2)).
Overall, the results of the ELIOT Trial are reasonably mature and encouraging.
Although there is a concern that generic measures may be less responsive than disease specific measures, the physical functioning and bodily pain scales of the SF-36 (which contribute most of the variation in the PCS summary measure used as the primary outcome in this trial) compare reasonably well with disease specific measures in patients with musculoskeletal problems [ 40- 43].
Although Michael Keegan, the MasterCard CEO, insists that "No effort has been spared in ensuring that the U.S. public's first experience of Mondex is a roaring success," and Mondex's promotional materials claim both trials are reasonably successful, the fact is that the trials have been a fiasco.
We also examined and compared 15 meta-analyses and review articles on homeopathy to ensure our collection of clinical trials was reasonably comprehensive.
A meta-analysis of these early trials confirmed reasonably high pooled sensitivities by patient and by lesion of 88% and 81%, respectively, with a pooled specificity of 95% for polyps 10 mm and larger [ 39].
For example, the odds ratios in the Lis and Jugdutt trials are reasonably similar, both of which are consistent with an approximate halving of risk in patients given intravenous nitrate, but the P value for the larger Jugdutt trial is substantially smaller than that for the Lis trial.
