Exact(4)
However, the small number of study subjects in this trial precludes a robust comparison on this point.
The limited number of evaluable patients in our trial precludes firm conclusions; however, several observations generate testable hypotheses.
Even if the sensitivity of the intervention trial precludes us from making any inference within the narrow range of regulatory limits, the trial data do provide a rigorous direct estimate of the upper bound to the risk from drinking water.
The follow-up period of only 1 month in each pacing mode in the IDEAL RVP trial precludes an assessment of the long-term consequences of each of the pacing modalities.
Similar(56)
But inequalities in blood pressure, favouring amlodipine, throughout the multiyear trial precluded comparison of outcomes.
Finally, this was an observational study and not an interventional clinical trial, precluding responsiveness analyses, including tests of sensitivity to change with treatment.
It is likely, however, that limited enrollment of advanced heart failure patients in the TIMI 11B trial precluded the incorporation of related variables into the final, seven-variable TIMI UA/NSTEMI risk score [2], [23], [25].
The MA.14 trial precluded robust comparisons with the unoptimized BCI.
Data on treatment administered after progression were not collected in this trial, precluding an exploratory analysis of the influence of subsequent therapy on OS.
A limitation of this study is that retinal photographs were obtained only at the end of the TODAY trial because the burdens and complexity of the clinical trial precluded baseline eye assessments (3).
The relatively few deaths (n = 15) and morbidities (n = 1) in this trial precluded precise estimation of DALYs, demonstrated by the wide confidence intervals around each of the point estimates.
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