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In that trial, pattern separation deficits improved in those MCI subjects exposed to the drug.
The same process was applied to the trial criteria to construct the trial pattern vector (Step 3).
Finally, the IE function computed the degree of match between the patient vectors and the trial pattern vector (Step 4) and output the ranked list of patients based on the matching scores (Step 5).
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The purpose of these two operations is to generate different trial halftone patterns locally (i.e., testing 3×3 trial patterns centered at the processing pixel).
Separately for each ROI, trial patterns were correlated with each other using Pearson's r.
Given the feeding trial patterns observed in this study, it is possible that a larva's initial exposure to specific host chemistry may determine its ability to detoxify subsequent novel compounds.
Further, in such trials, pattern separation tasks could serve both as a proof of mechanism and an efficacy measure.
During the 1980s and 1990s, prior to the more recent trials, practice patterns showed increased use of thrombolytic therapy and PCI, and decreased use of CABG in many geographic areas [ 27- 31].
However, as winning trials were explicitly separated from losing trials, the pattern of activation is unlikely to reflect engagement in anticipating losses or punishment rather than receiving rewarding stimuli.
Variation between number of trials per pattern and selection of the middle pattern trial was conducted to prevent the possible confound of the participants expecting a pattern shift in later win trials and thus demonstrating decreasing win expectancy as pattern shifts became more likely due to a high number of consistent wins.
Although the difference in number of males courting females across treatments was just non-significant (p = 0.053) during the Female Experience trials, the pattern is consistent with a highly significant difference observed during the Search and Choose trials (below).
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