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These differences may partly account for the reduced capacity of chronically immune activated individuals to mount effective immune responses and strengthen the notion that the host immune background should be considered in the design and trial of potential adjuvants and vaccines.
The ISG had taken on a deliberately broad remit, integrating scientific questions with policy considerations: they had described the RBCT as "a trial of potential culling policy options" (Bourne et al. 2007, p. 38).
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BMS's revenues, like AstraZeneca's, are still roughly flat, but the excitement is generated by the progress in trials of potential cancer drugs.
Dr. Charash helped direct the growth of our clinic program to more than 200 hospital-affiliated clinics across the country, and was a key figure in the expansion of our worldwide research program, leading to significant advancements in the understanding of neuromuscular diseases and to present-day clinical trials of potential treatments.
Another goal of current efforts is to expand the local capacity for clinical trials of potential vaccines and malaria treatments.
One final stock making gains in this rough market is Covance, which develops and carries out preclinical and clinical trials of potential commercial drugs.
Chronic disease prevalence and burden is growing, as is the need for applicable large community-based clinical trials of potential interventions.
Since the initiating events that result in the cartilage degradation are poorly understood, there has been very limited success in demonstrating disease modification in clinical trials of potential therapies.
Biomedical researchers are sure to find a lot to like about CIRM 2.0, especially Mills' commitment to streamline the program's grant and loan approval process for projects aimed at clinical trials of potential therapies.
This development allows the in silico investigation of pathological mechanisms and the trialing of potential treatments.
Such techniques may therefore provide a useful adjunct to clinical assessment in monitoring disease progression in therapeutic trials of potential disease modifying therapies.
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