However, a limitation of this study was that the manipulation of reward occurred only in a blocked rather than trial-by-trial manner.
Thus, an optimal experimental design for identifying and potentially dissociating sustained from transient motivational effects is one in which rewards are manipulated in both a block-based and trial-by-trial manner.
And while Paterno is on trial in some manner, he obviously is not charged, and never was.
Orhan Cengiz, a human-rights lawyer who supports the indictment, described the Ergenekon trial in this manner: "This is the first time in Turkish history that prosecutors and police found themselves dealing with crimes that indicted the military.
Murray's "callous disregard for Mr Jackson's health and safety was shown throughout the trial, from the manner in which he administered a number of dangerous drugs to Mr Jackson without the appropriate medical equipment, precautions or personnel in place, and to the manner in which he left Mr Jackson unattended", the opinion states.
In order to get a solution that satisfies individual preferences, existing algorithms are consecutively applied in a trial and error manner.
In the same manner, trial sequential monitoring boundaries can be applied to meta-analyses.
When a P cue appeared on the contralateral side, neural activity in the amygdala predicted whether or not the monkey would later abort the trial in a manner dependent upon the reward selectivity of neurons.
In proposing the imperative of clinical equipoise for the conduct of a RCT, Freedman [ 2] also emphasized the need for designing and conducting the trial in a manner that ensures that equipoise will be disturbed if one of the comparator interventions is indeed superior.
A review of outcomes of breast cancer therapies [ 1] evaluated all therapeutic regimens known to be effective in randomized trials in stage IV breast cancer, and then tested in an identical manner trials in the adjuvant setting of breast cancer - the 'doubly tested trials' (Table 1).
Trialists have an ethical and financial responsibility to plan and conduct clinical trials in a manner that will maximize the scientific knowledge gained from the trial.
