Sentence examples for trial knowledge of from inspiring English sources

For any intervention trial, knowledge of the natural history of the disease and process of care informs the design and conduct of the trial.

The guide queried reasons for joining the trial, knowledge of TB, why isoniazid prophylaxis is important for persons infected with HIV, barriers to trial participation, adequacy of information provided about the trial, perception of the care and treatment provided by trial staff, benefits of being in the trial, and reasons participants stopped taking the study pills.

"What is needed is know-how of criminal trials, knowledge of international law and overall management skills," he said.

Sample size calculations for clinical studies are usually conducted to determine the total number of patients needed to satisfy a specified power requirement, and their validity is dependent on pre-trial knowledge of nuisance parameters and distributional and modelling assumptions.

In the absence of randomised controlled trials, knowledge of outcomes associated with medication use during pregnancy is dependent on observational studies.

In the design of clinical trials knowledge of the temporal relationship between HbA1c and diabetic complications is essential so that an appropriate study length is chosen and an improvement in glycemic control can lead to beneficial effects on diabetic complications.

If confirmed in future trials, knowledge of these factors may help to improve discharge management and avoidance of prolonged hospitalizations due to non-medical reasons.

Selection of an appropriate patient-reported outcome (PRO) instrument for a clinical trial requires knowledge of the instrument's responsiveness to detecting treatment effects.

In a clinical trial, the knowledge of instrument's responsiveness helps in the selection of measures, in setting the correct sample size and assists in prioritising the number of outcomes to be assessed.

Box 4, on blinding terminology, defines the groups of individuals (that is, participants, healthcare providers, data collectors, outcome adjudicators, and data analysts) who can potentially introduce bias into a trial through knowledge of the treatment assignments.

The implication of medical exclusion on case diagnosis is not known and determining the representativeness of participants selected for trials requires knowledge of disease prevalence in the general population and in individuals with MCI.