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As outlined in the trial justification, the supply of primary health care in the trial area is inadequate.
HDL-size and HDL-p, assessed using the LipoScience ALP method, were compared to classical biochemistry measures of HDL-c and ApoA1 in 10,886 participants without CVD in the JUPITER trial (Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin) [56].
The JUPITER trial (Justification for the Use of statins in Primary prevention: an Intervention Trial Evaluating Rosuvastatin) is a statin-based trial that targets individuals with high CRP levels and initial low LDL cholesterol levels (LDL cholesterol <130 mg/dl (<3.36 mmol/l) and high-sensitivity CRP ≥2 mg/l) in primary prevention of cardiovascular outcomes (35, 36).
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It also means freedom from coercion: freedom from databases, identity cards, iris scans, fingerprints, random searches, imprisonment without trial or justification.
Given the high mortality associated with AKI, the lack of specific RRT interventions shown to reduce mortality, and current practice variation, the results of our pilot trial provide justification for a larger trial of hemofiltration vs. hemodialysis that will be adequately powered to evaluate meaningful clinical outcomes.
The generally positive response to the film suggests to the writer that one generation after the Nuremberg trials, any justification of survivorship under Fascism seems to have become acceptable.
Only 5/38 (13.2%) of the trials provided justification for the predicted delta.
The data extraction form was developed based on Jones et al. [ 8] to include data on whether systematic reviews were referenced and used in the design of trials for justification of treatment comparison, choice of frequency or dose, selection of an outcome, withdrawals or adverse events etc (refer to Jones et al. for a full listing).
"I feel we need to muster the support of our patients and lobby both Roche and the F.D.A. Compromising the Phase III trial is not justification for withholding an effective drug from dying patients".
1 4 As incontinence is associated with multimorbidity and other deleterious health effects, results from this trial provide strong justification for public health outreach via community organisations to reduce urine leakage among untreated individuals.
8 A recent clinical trial, ie, JUPITER (Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin) demonstrated that rosuvastatin 20 mg daily significantly reduced the incidence of major cardiovascular events (CVEs) and all-cause mortality among individuals without hyperlipidemia but with elevated high-sensitivity C-reactive protein levels.
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CEO of Professional Science Editing for Scientists @ prosciediting.com