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The trial is terminated when either the highest dose that can be given to humans with acceptable side effects has been reached or, in the absence of side effects, an effective dose has been achieved.
If the O'Brien-Fleming monitoring boundary is exceeded the trial is terminated.
A lower limit α0 can be included so that the trial is terminated without rejecting H0 if p1 ≥ α0.
The trial is terminated if the maximum sample size is reached, p1 > P h, or p2 + p3 > P i.
If both dose levels are considered to be excessively toxic, the trial is terminated; if only the high dose level is toxic, then this dose group is closed.
50 A trial is terminated early if either the inclusion or the follow-up is terminated earlier than foreseen in the research protocol.
Similar(50)
Mr. Perino, who opted for a nonjury trial, was terminated by the Police Department after his conviction, said Paul J. Browne, the chief police spokesman.
This trial was terminated early due to low enrollment.
However, despite accurate targeting of the therapeutic to CD44, this trial was terminated due to graded dose-related dermal toxicities.
Participants searched the image for a change or until 40 s had passed, at which point the trial was terminated.
The trial was terminated early due to an imbalance in rate of serious infections in the ocrelizumab group receiving MMF.
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CEO of Professional Science Editing for Scientists @ prosciediting.com