Weaning failure was defined by the T-trial intolerance or need for reintubation in the first 48 hours after extubation.
Two pilot studies performed in patients who initially failed an NIV trial due to intolerance and therefore met ETI criteria showed that the administration of remifentanil removed the need for intubation in most of the patients [ 31, 32].
Reasons given were non-medical (such as moved to another city, n=15), presumed lack of benefit (n=10), symptom free (n=2), and intolerance of trial treatment (n=34; 7 patients allocated to psyllium, 18 patients allocated to bran, and 9 patients allocated to placebo).
Intolerance is intolerable.
And this list is disrespect for the rights of others, willingness to kill without a trial, aggression, and [INAUDIBLE] AUDIENCE: Intolerance.
Wang, from Human Rights Watch, said Xu's trial and sentence underlined increasing intolerance for dissent since Xi Jinping took over as president last year, and the hypocrisy inherent in Xi's supposed commitment to fight corruption.
Contraindication or previous intolerance to any trial therapy.
An assumed 10% drop-out rate in this trial (due to non-compliance, intolerance, etc).
Trial results indicate that initial intolerance owing to GI side-effects is transient, and that once tolerance is achieved, compliance is easier to maintain.
A pilot study previously undertaken by the SoLID research group showed good tolerance to lower dialysate with minimal adverse events, and we do not anticipate excess loss of participants due to intolerance of the trial intervention [ 89].
