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QTL analysis was performed for each trial individually, using a composite interval mapping (CIM) approach in WINQTLCART v.2.5 software (Basten et al. 2005).
Tanzanian participants were recruited to the trial individually when they presented to routine services with malaria symptoms for which they sought a cure.
In placebo controlled trials lasting up to 12 weeks, no trial individually reported a significant difference, nor was there a difference when trials were combined.
Although neither trial individually demonstrated a statistically significant difference favouring pegaptanib over sham (figure 5), when pooled together in meta-analysis, a statistically significant difference was found in favour of pegaptanib (OR 1.94, 95% CI 1.01 to 3.71).
When comparing SOD and GPX activities before and after the feeding trial, individually for each group of growers, the results of statistical analysis (paired t-test) showed significant difference in SOD activity only in the group that was fed basal diet with added acids and tannin (Group III).
Comparison of the results before and after the trial, individually for each group of growers (paired t-test), showed statistically significant increases of RBC, Hgb, Lymph and Eos, and decreases of MCV, Plt, WBC, Neut, in all three groups of growers.
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While none of these trials individually showed a significant mortality benefit, when combined in an individual-patient meta-analysis the patients with moderate-severe ARDS (PaO2/FiO2 ≤ 200) had lower mortality and more ventilator-free days with higher levels of PEEP (approximately 15 cmH2onon day 1) [ 44].
Time-trial Individually timed over a set course; drafting is banned.
Ten trials individually assigned patients to intervention groups and two randomized 31 clinics with 103 nurses.
We found no significant differences between groups for the trials individually (0.45 (−0.11 to 1.01 w1 and −0.04 (−0.17 to 0.09 w6).
The participants completed eight blocks of 64 trials individually under normal fluorescent lighting in a soundproof room.
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