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Adaptive trials allow the preplanned modification of key clinical trial characteristics during the trial implementation phase based upon new information acquired within the trial itself and a set of carefully simulated rules (for example, changing the number of treatment arms, available dosing levels, randomization ratios and inclusion/exclusion criteria).
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A different design would be required for an implementation (phase IV) trial.
During the design and implementation phase of this trial, unanticipated challenges arose, requiring flexibility to address them.
The guided implementation phase comprised 12 correct trials, including three repetitions of four distinct S R O triples (termed S R O repetition in the following discussion).
The trial involved a design and testing phase and an on-ground implementation phase.
The final Implementation phase of Think Big Analytics is twofold.
The new Digital Technologies curriculum will provide challenges for teachers in its early implementation phase.
Weaver said the news was a sign that the Paris pact "needs to come out of discussion phase and really into the implementation phase".
This guided implementation phase was followed by an unguided implementation phase in which the IS was omitted, which comprised another 20 correct trials (i.e., five repetitions of the four distinct S R O triples).
The policy implementation phase was also challenging.
Trial implementation will also be examined.
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