My compatriot in mental health advocacy, Liza Long, was surprised at my strong reaction given how the trial had progressed.
Patients recruited to this trial had progressed after four or more cycles of platinum-based doublet chemotherapy and had not received prior EGFR-TKI therapy.
The Federal National Mortgage Association and Freddie Mac approved and even initiated programs to reduce homeowner debt and save taxpayers millions, but halted them before the trials had progressed far enough to measure success, according to documents released Tuesday.
Since its beginnings in the 1960s, the design of modified atmosphere packaging (MAP) has progressed from a trial and error process to one that is firmly based on sound phenomenological models developed with a good understanding of the underlying mechanisms.
Reports on 11C- and 18F-labeled gefitinib imaging in tumor-bearing mice indicated that [11C]gefitinib has more potential than its fluorine-18-labeled congener, although to date, neither has progressed into clinical trials [26,29].
Over the last 20 years, there has been a large amount of research directed toward the development of a multitude of nanocarriers for drug and gene delivery, but only a very small part has progressed into clinical trials.
As introduced above, odanacatib (46, Fig. 8) has progressed to clinical trials for osteoporosis.
There is at least one small molecule (MGCD 290) that inhibits Hos2 histone deacetylase that has progressed to clinical trials.
Finally, KLH has progressed into clinical trials as either adjuvant- or immunomonitoring tool in a variety of vaccines directed against cancer [ 4, 5] or infectious diseases [ 6].
