Exact(2)
Only the AOSpine NA GOF trial fulfils this requirement [ 49].
The trial fulfils the criteria set out in the Consolidated Standards of Reporting Trials (CONSORT) Statement for Randomised Trials of non-pharmacologic treatment guidelines [ 26, 27].
Similar(58)
This manuscript describes the rationale and design of a pragmatic cluster-randomised, crossover trial to fulfil this need for evidence.
Continuing monitoring of the trial to fulfil these progress reporting is now obligatory.
Firstly, an adequately powered randomised controlled trial would fulfil a methodological recommendation that has consistently been made in systematic reviews of the extant literature.
These data make it clear that the trial participants' ability to fulfil the activities of daily life is much lower than that of the general population.
A referral form has been drawn up, to be filled in by the GP requesting inclusion in the trial of patients who fulfil the selection criteria.
Trial patients had to fulfil ACR criteria for fibromyalgia and have pain scores of ≥ 40 mm on the 100 mm visual analogue scale (VAS) after stopping any relevant pain or sleep medication.
To be responders to a modified American College of Rheumatology Pediatric (ACRpedi) 30 score built for the purpose of the trial, patients had to fulfil the three following conditions: (1) ACRpedi 30 response 15; (2) absence of disease-related fever (body temperature <38°C over the past 8 days) and (3) 50% decrease compared with D1 or normalisation of both CRP and ESR values.
Results from three replicated experimental inoculation trials conducted to fulfil Henle-Koch's' postulates and determine the virulence of putative pathogens by causing mortality to infected corals are presented in table 2. Healthy colony fragments exposed to putative pathogens P1 P6 (1×106 cells ml−1) displayed signs of disease similar to those observed in the field in all experiments (Fig. 2A F).
Of note, the majority of the patients in these trials did not fulfil the modified New York criteria for AS.
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