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No controlled trial fulfilling eligibility criteria was identified.
In summary, this is the first trial fulfilling the highest recommended methodological standards regarding the primary outcome measurement (JS loss) and its statistical analysis.
Our experiments have demonstrated that it is possible to produce enough genetically corrected autologous transplants from a single human epidermal stem cell for a pilot clinical trial fulfilling strict safety criteria.
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Following trial completion, the "opinion leaders" who designed and ran the trial fulfill their obligation by organizing "scientific symposiums" that present the trial results with great fanfare -- complete with free food, wine, entertainment and no dissenting viewpoints.
Once we have confirmed that the clinical trial fulfills these criteria, we need to determine whether the results can be applied in our environment and whether the benefits obtained justify the risks and costs involved.
No trial fulfilled all the quality criteria assessed.
All patients included in the trial fulfilled the modified New York Criteria for definite diagnosis of AS, which serve as the basis for the ASAS/EULAR recommendations [ 24].
The SEAMLESS trial fulfills a great need as it strives to provide access to potentially effective therapy to patients over 70 years old.
The vaccine used in our trial fulfilled all international licensing criteria in both the adult and elderly age-groups [ 24, 25].
However, the renal outcomes on diabetic nephropathy from therapy of ACE inhibitor plus calcium channel blocker could not be evaluated in our current analysis since no available trial fulfilled our inclusion criteria.
Women considered participants in this trial fulfilled the following criteria: aged 18 42 years at the time of interview; a history of ≥2 unexplained consecutive pregnancy losses before 20 weeks gestation; persistent presence of anticardiolipin antibodies and or Lupus anticoagulant in two occasions 8 weeks apart.
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CEO of Professional Science Editing for Scientists @ prosciediting.com