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Our findings provide the first high quality evidence from a randomised controlled trial for the development of universal guidelines and support the British Thoracic Society's recent guidelines on acute oxygen treatment, which recommend that oxygen should be administered only at concentrations sufficient to maintain adequate oxygen saturations.
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Preclinical and clinical trials for the development of new diagnostics and therapeutics as well as prevention efforts are covered whenever possible.
In summary, preclinical trials for the development of novel therapies for stroke should include large and complex cohorts of animals and include sex-mixed, aged animals from different strains, ideally with different comorbidities.
This review provides an overview of clinical trial designs for the development of tumour vaccines and targeted therapeutic agents.
A workshop evaluating potential trial designs for the development of therapies for localized prostate cancer was held in San Diego, CA, in May 2013.
To summarize the discussion at a public workshop, cosponsored by the U.S. Food and Drug Administration FDAandand the American Urological Association, reviewing potential trial designs for the development of new therapies for non muscle-invasive bladder canon muscle-invasive
Discuss issues regarding clinical trial design for the development of biosimilars in the European Union and the United States, with special focus on monoclonal antibodies used in the treatment of inflammatory diseases.
Randomised control trials (RCTs) for the development of policy have been a feature in Welsh policy-making for some time.
These findings should provide important guidance for ongoing human trials, especially for the development of suitable T cell biomarkers.
This may be in part because frozen tissue samples have rarely been archived from patients in clinical trials suitable for the development of predictive signatures.
FvdV, MW, and BMW designed the trial, were responsible for the development of the protocol, applied for a grant and have overall responsibility for the trial.
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