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The RT assay has not been evaluated in a longitudinal field trial for monitoring patients on ART in RLS.
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It has been used in innumerable clinical trials for monitoring the change in mood state over a period of time.
Another approach to the design of phase II trials for monitoring survival probabilities would be to use parametric methods.
Committees continue to face various capacity needs especially for evaluating clinical trials, for monitoring ongoing research, database management and for accrediting institutional ethics committees.
We have shown how results described by Lin et al [ 21] could be used to design efficient phase II trials for monitoring survival probabilities.
The committee is responsible for safeguarding the interests of trial participants, assessing the safety and efficacy of the interventions during the trial, and for monitoring the overall conduct of the clinical trial.
It is responsible for safeguarding the interests of trial participants, assessing the safety and efficacy of the interventions during the trial and for monitoring the overall conduct of the clinical trial.
Where an instrument is required for use in a clinical trial or for monitoring individual patients, a high reliability is desirable (that is, a correlation coefficient of at least 0.85) [ 26].
Biomarkers may have particular utility in selecting appropriate patients for inclusion in clinical trials and for monitoring therapeutic response.
HPV typing is also very important for characterization of the population in HPV vaccination trials and for monitoring the efficacy of HPV vaccines [ 13].
The information derived by this study will have an impact on the immediate translation of HDACi in the pharmacological treatment of DMD patients, as it indicates cellular targets and mechanism of action that will help to the identification of new biomarkers for patient selection in clinical trials and for monitoring the efficacy of the intervention.
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