For instance, some pointed at the lack of information on the tolerance levels of normal organs as an obstacle for clinical implementation of dosimetry, while others argued that prospective, randomized trials for examining the clinical value of dosimetry are needed before implementation.
One caveat of applying quantile regression in clinical trials for examining HTE is that QTE doesn't demonstrate the treatment effect for a given patient.
We conducted a randomised controlled trial (RCT) for examining the feasibility of a 4-month home-based, exercise-training program designed based on recent physical activity guidelines for MS and supplemented by behavioural strategies for compliance.
A standardized quantitative method for comparing dosages of different drugs is a useful tool for designing clinical trials and for examining the effects of long-term medication side effects such as tardive dyskinesia.
This enables comprehensive analysis of the relationship between intervention use and symptom reduction following the trial, for instance, examining dose response curves and whether viewing some sections in particular appeared to be critical to beneficial outcome.
Analyses will be undertaken using mixed-model repeated measures (MMRM) which is the recommended method for examining clinical trial data [ 75].
With data collected regarding previous habits, use at registration, and again following completion of treatment, this trial provides an ideal basis for examining the use of vitamin supplements before diagnosis and during chemotherapy, and the extent to which discussions with patients' physicians influenced patterns of usage during treatment.
Randomised controlled trials are the "gold standard" for examining the efficacy and safety of medical interventions because they are considered free from bias.
We performed our studies on 162 patients with rectal cancer after preoperative short-term radiotherapy recruited from January, 2008 to September, 2011, for trial examining the role of gentamicin collagen implant (GCI) in the risk of cancer recurrence.
The PEX study protocol published by Van Linschoten et al. [ 9] served as the model for this trial because it is a high-quality protocol for a trial examining an intervention for patients with a PFPS.
