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GlaxoSmithKline officials have denied that they selectively disclosed trial findings.
The new trial findings show that administering rituximab early, alongside methotrexate, can virtually stop the disease in its tracks.
Without an optimized design, the applications of the trial findings are uncertain.
The major in vitro, in vivo and clinical trial findings have been summarized here.
The industry's trade group, the Pharmaceutical Research and Manufacturers of America, has also started a Web site where drug makers can post trial findings.
Evaluation of the robustness of statistically significant outcomes adds a crucial element to the global assessment of trial findings.
Without transparent reporting, readers cannot judge the reliability and validity of trial findings nor extract information for systematic reviews.
Premature discontinuation causes loss of information, potentially resulting in attrition bias leading to problems during interpretation of trial findings.
To better understand intervention trial findings, we asked participants about their intervention experiences and examined potential contamination across arms.
As a signer, the United States could help nominate judges and prosecutors, and ensure that the court's elaborate machinery for preventing politically biased trial findings be maintained in practice.
Mr. Spitzer has previously said that he planned to use legal action or the threat of legal action to force greater industry disclosure of clinical trial findings, an issue that has drawn intense public interest.
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CEO of Professional Science Editing for Scientists @ prosciediting.com