Future cluster randomised trials should endeavour to either identify participants before randomisation or use an independent person, preferably blind to allocation, to recruit participants.
Rather, sites with clinical trial capacity should endeavour to share resources (skills, laboratory capacity, community engagement efforts) to reduce the opportunity costs of a single trial with a long-term developmental agenda in mind.
The contribution of life sciences to the Knowledge-Based Bioeconomy (KBBE) asks for the transition of contemporary, gene-based biotechnology from being a trial-and-error endeavour to becoming an authentic branch of engineering.
Before guidelines can be revised, there is a case to be made for seeking robust clinical trial evidence, a scientific endeavour currently undertaken by the Randomised Ambulatory Management of Primary Pneumothorax study (RAMPP) [10].
Still, Sercarz noted that bringing a rape case to trial is a complicated endeavour, because district attorney offices tend to act on cases only when they feel likely to succeed in getting a conviction.
Recalling the Judea, the bark on which he served as second mate, Marlow says that, to him, it was not "an old rattle-trap" but "the endeavour, the test, the trial of life".
All trial staff and investigators will endeavour to protect the rights of the trial participants to privacy and informed consent, and will adhere to the Data Protection Act, 1998.
The trial was the result of Operation Endeavour, a joint police and Gangmasters Licensing Authority investigation launched to tackle concern about the widespread exploitation of migrant workers and growing associated organised crime in the Fens.
Given that so much of this endeavour occurred at the main trial stage, we mainly identified learning for future trials.
