Sentence examples for trial dose from inspiring English sources

These experimental designs should better inform next-step radiation-agent clinical trial dose, schedule, exposure, and therapeutic effect.

Design/Method: As part of a previously published, active-control, LTG monotherapy trial, dose and plasma concentration data for LTG, carbamazepine (CBZ) or phenytoin (PHT) were obtained.

For all subjects, regardless of outcome or length of trial, dose was not correlated with CYP2D6 or CYP2C19 metabolizer status (see Table 3).

In the trial, dose escalation was given to overcome the loss of clinical efficacy.

We normally take 500 pg mRNA/embryo as a trial dose for injection.

All horses were administered dobutamine during each trial (dose range 0.5-1 μg/kg/min).

For pharmaceuticals, systemic dose data are generated routinely in nonclinical safety studies very early in the toxicity testing program and play a major role in the selection of clinical trial doses.

In the phase 2 bapineuzumab trial, dose-related vasogenic edema (ARIA-E) was observed [ 20].

In the Intergroup/CALGB 9741 trial, dose-dense doxorubicin, cyclophosphamide and paclitaxel significantly improved disease-free survival (DFS) compared with conventional dosing [ 2].

For ethical reasons, in this trial, dose-finding is conducted in children with normal G6PD status, but, ultimately, information is needed on the safety of lower doses in people with G6PD deficiency.

In the BAFTA (Birmingham Atrial Fibrillation Treatment of the Aged) trial, dose-adjusted warfarin with a target INR of 2.5 was compared with acetylsalicylic acid 75 mg/day in patients aged > 75 years in the primary care setting.