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One woman in the intervention group and three women in the control group used SSRI/SNRI medication during the trial (difference not significant).
It was then suggested that, in the Leuven trial, difference in observed mortality was secondary to a higher mortality in the control group due to an excessive glucose load.
We repeated the 'effort minus delay trial' difference analysis, having first performed a median split of DLPFC neurons into those with high and low response-selectivity (Author response image 1).
On the contrary, the strong effect of interference showed in the delayed trial (difference of performance between trials 6 and 7) is not associated with age but is a specific characteristic of the impaired groups.
The RE-LY patient population is also slightly more inclusive of AF patients eligible for anticoagulant treatment, than the population in the ARISTOTLE trial (difference of 3%; p<0.001) but this statistically significant difference between the RE-LY and ARISTOTLE populations would not necessarily translate into clinically meaningful differences for the real-world population.
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To compare, in a prospective, randomised controlled trial, differences in anal sphincter function following forceps or vacuum assisted vaginal delivery in an institution practising standardised management of labour.
Adjustments for trial differences will be made by including the trial variable in the model specification.
Due to the randomized nature of this trial, differences in baseline QoL with respect to treatment arms are unlikely [ 14].
Binary outcomes will be analysed using log-binomial regression models adjusting for trial differences by including the trial variable in the model specification.
Home oxygen therapy Binary outcomes will be analyzed using log-binomial regression models adjusting for trial differences by including the trial variable in the model specification.
If we excluded activity from the first three months of the trial, differences in the admission proportion would not have been significant under any of the models.
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