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The CONNECT advisory group and EcLiPSE trial development team developed and reviewed an interview topic guide and draft EcLiPSE PIS.
Management guidelines have been developed through the clinical trial development process for ipilimumab and tremelimumab (Table 2) 33, 33 and strongly advise initiation of corticosteroids in any patient treated with ipilimumab in which an irAE event is suspected.
At the time, her institution was developing its own immersive course in clinical trial development, which she participated in.
We hypothesised that, compared to usual care, a CMHT-based nurse led intervention would increase the rate of screening for cardiovascular risk factors in people with SMI We undertook trial development work in line with the existing UK Medical Research Council framework for developing a complex intervention such as this [ 23].
38– 40 An expert panel recently developed a consensus definition for cisplatin ineligibility for the purposes of clinical trial development, although these criteria are applicable to clinical practice as well (Table 1).
Neurocognitive assessment in the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) project schizophrenia trial: development, methodology, and rationale.
Increasingly established scientific principles, including directional modulation of well-informed cortical targets, are advancing clinical trial development.
In this article, we review the clinical trial development of second-generation IMiDs lenalidomide and CC-4047.
High-fidelity patient simulation centers provide an ideal environment to apply human-centered design to clinical trial development.
Furthermore, we will discuss criteria guiding clinical, radiographic, and immunologic parameters with respect to clinical trial development in neuro-oncology.
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Trial entry criteria changed as did the cut-off for mandatory discontinuation in the event of the on-trial development of severe, uncontrolled hypertension.
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