Corrective feedback (i.e., "Well done!" and a tick for a correct response, or a "dong" and a cross for an incorrect response) was only given for catch trials (continuum endpoints).
However, the distinction between the two types of trial is a continuum rather than a dichotomy, as it is likely impossible to perform a pure efficacy study or pure effectiveness study.
The same order was presented twice for each pair, yielding a total of 56 trials for each continuum.
The traditional "learn confirm" paradigm is predicated upon learning gained in phase I/II evaluations in healthy volunteers and targeted patients and confirming in late-stage trials providing a continuum for MIDD.
The model contains seven fixed variables: Trial (1 112), Block (1 3), Continuum Step (1 7), Talker.Voice (male vs. female), Vowel (/a/ vs. /u/), Subject.Sex (male vs. female), and total AQ (50 200).
This effectiveness RCT continues along the translation continuum by trialling the sleep intervention in 'real-world' settings, that is, delivered by primary school nurses through the existing school health screening and intervention framework.
Although participants discussed additional text for item 1 of the checklist (title/abstract), principally adding the word pragmatic to the title or abstract, we decided against making this recommendation because it may reinforce the misconception that there is a dichotomy between pragmatic and explanatory trials rather than a continuum.
However, within this document we will use the more general terms "efficacy" and "effectiveness" to label both ends of the continuum and a trial that is more on the effectiveness side would be a pragmatic trial.
This will be influenced by the location of the trial along the pragmatic-explanatory continuum [ 18].
We analysed the ACCESSATION Study trial design elements on a continuum using the qualitative, multidimensional PRECIS tool.
