Exact(20)
In combination with several molecular profiling techniques, the "Mouse Avatar" and Co-clinical Trial concepts have the potential to revolutionize the drug development and health care process.
Results indicate the need for targeted education programs that adequately inform IDUs about clinical trial concepts prior to recruitment to a clinical trial, and support adaptations of informed consent procedures to ensure trial participants' comprehensive understanding of methodologies and their implications.
Following detailed verbal explanations, higher proportions of trial-experienced than trial-naïve participants demonstrated an understanding of all clinical trial concepts assessed, including single blinding (94% versus 60%); placebo (94% versus 49%); equipoise (71% versus 60%); comparison (59% versus 46%); randomisation (59% versus 21%); and double blinding (47% versus 3%).
All informants participated in a series of educational sessions on HIV, AIDS and HIV vaccine trial concepts and procedures that were conducted from 2006 to 2007 among potential volunteers for the HIV vaccine trial [13], [20].
Topics included general research concepts, general vaccine trial concepts, and concepts unique to HIV vaccine trials.
Use of vignettes in explaining the trial concepts and research [ 35].
Similar(40)
XG and MC developed the trial concept and design.
MM, JH, RE, GB, KW participated in the initial trial concept.
CJH, LS, AJC and DL all contributed to the trial concept and design, interpretation of data and drafting of the manuscript.
YK, DG, AAK, SK, and AT all contributed to the trial concept and design, interpretation of data and drafting of the manuscript.
Check out AVAC's HVAD 2013: The Countdown Continues, which includes snapshots of AIDS vaccine research, trials, concepts, volunteers, sites and funding, along with a timeline of key milestones over the past 25 years.
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