The SCOPE Intervention Study is a cluster randomized, three-armed controlled trial complemented with a qualitative study.
Pathway analysis (incorporating decision tree analysis) will be used to clearly identify the activity components for each arm of the trial, complemented by a prospective patient-held cost diary covering the entire trial period (week one to 24 months).
The design consists of a pragmatic multi-centre, three-armed randomised controlled trial, complemented with an economic evaluation of the results achieved, comparing the effectiveness of verum acupuncture with sham acupuncture, and with a control group receiving normal care only.
The pattern observed in the ERF analysis of same-speaker deliberation trials complements and corroborates our results based on theta power and phase-coherence.
Organoid technology may fill the gap between cancer genetics and patient trials, complement cell-line- and xenograft-based drug studies, and allow personalized therapy design.
Nevertheless, pilot-scale trials complemented with sensorial analysis of the produced wines are required for a full evaluation of our strain's potential for its application in the wine industry.
This manuscript illustrates the results of combining irradiation and an anti-EGFR antibody in a double blind trial that complements the nimotuzumab add-on to temozolomide/irradiation study in GBM, which is underway under a German sponsorship in Europe [ 23].
The trial was complemented by a large-scale, primarily qualitative, process evaluation.
Jubran and colleagues [ 62] showed that the esophageal pressure trend during a spontaneous breathing trial (SBT) complemented the prediction of weaning outcome provided by the frequency/VT index measured during the first minute of an SBT.
It will evaluate the design, implementation, mechanisms of impact and contextual factors that create different intervention effects in this study in order to develop an optimal community sport intervention and to contribute to decision-making about whether it is feasible to proceed to a larger scale trial by complementing the outcome and economic evaluation.
