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The literature search and screening process identified 13 publications with 24 treatment trial comparisons and 18 prevention trial comparisons.
Maybe we are expect to carry out deeper simulation research and trial comparisons.
The use of standardized outcome measurements is encouraged to facilitate meta-analyses and between trial comparisons.
Ferumoxytol was first approved for clinical use in 2009 solely based on data from trial comparisons with oral iron on biochemical anemia efficacy end points.
In each trial, comparisons were made between intensive and moderate arms for both trials' primary end points and death/myocardial infarction.
There were 20 trial comparisons (Table 2).
Similar(25)
Because there are limited head-to-head data comparing antiretroviral combinations, physicians are tempted to rely on cross-trial comparisons to evaluate the relative efficacy of HIV drugs.
However, differences in patient populations, comparators, and selection and/or definition of secondary endpoints make it difficult to draw direct cross-trial comparisons.
At this point, one should note that for trial-by-trial comparisons between methods only those against GCT are present for the sake of conciseness.
Taking GCT as a reference, trial-by-trial comparisons of iPDC and cMVGC, respectively, confirm the pattern of higher FP for the former compared to a pattern of FP, below 1%%, for cMVGC with or without correction (See Figs. 13, 14).
This makes cross-trial comparisons difficult [ 30– 30].
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CEO of Professional Science Editing for Scientists @ prosciediting.com