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No modifiers were found when adjusting for the following variables: proportion of men (coefficient, −0.074; p=0.08), mean age of treated patients at inclusion (coefficient, 0.020; p=0.94), mean age of untreated patients at inclusion (coefficient, 0.121; proportionroportion with cirrhosis at inclusion (coefficient, −0.001; p=0.76) and region of trial (coefficient −0.394; p=0.55).
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Estimated breeding values for BFT were calculated in the population using a BLUP-Multiple Trait-Animal Model that included the fixed effect of sex (considering the triplets of pigs from the same litter), batch on trial, inbreeding coefficient of the animal, interaction of sex by age at slaughtering, date of slaughtering and random effect of litter and animal.
Angel's pull-step ratio increased across successful trials (Regression coefficient = 13.46: t1,3 = 5.298, p = 0.013).
In a two-centre clinical trial setting, the coefficient of variance for ADC measurement in the body was approximately 7% (coefficient of repeatability 14%).
In trial 2 the coefficient of ileal apparent digestibility (CIAD) of dietary components, the pH of the gastro intestinal tract (GIT) and the weight of digestive organs and spleen were measured at 48 days of age.
In the corresponding sections the total cluster required to achieve a cluster trial with a coefficient of 80% are reported to a two-tailed alpha error of 0.5 and an a hypothetical ES of 0.4.
Experimental error was low in each trial, given the coefficient of variation (CV) values of 5.77% in the MD experiment and 5.99% in the NE experiment, with an overall CV of 5.67% in the 2-location analysis.
Through repeated trials, a viscosity coefficient of 0.0005 was found to give better results.
Through extensive trials, a viscosity coefficient of 0.0005 was found to be helpful with convergence.
Within trial intraclass correlation coefficients (ICCs) ranged between 0.90 and 0.99 and the between trial ICC values ranged between 0.02 and 0.96.
A 20-week controlled feeding trial obtained calibration coefficients (CC) for P. orbignyanus fed two types of prey (silverside and menhaden).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com