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PePiTA is a prospective, multicenter, non-randomised trial built on the hypothesis that preoperative chemosensitivity testing using FDG-PET/CT before and after one course of FOLFOX can identify the patients who are unlikely to benefit from 6 months of adjuvant FOLFOX treatment for stage III colon cancer.
The trial built on two decades of work by Professor John Greenwood at the UCL Institute of Ophthalmology.
Currently a randomized clinical trial built on the results of the feasibility study and funded by a national grant is accruing participants.
We now embark on a randomized, blinded, sham-controlled school environmental intervention trial, built on our extensively established school/community partnerships, to determine the efficacy of a school-based intervention to improve asthma control.
This trial built on cumulative experience from the prior decade of indeterminate trials [ 10– 15], which served to refine the target population, intervention strategy, and co-interventions.
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This trial builds on formative and pilot research findings.
The APOE4 trial builds on another trial of an anti-amyloid drug in 300 members of a Colombian family who carry a gene mutation that places them at high risk of developing an early-onset form of Alzheimer's disease.
"This trial builds on our recently announced PayPass Wallet Services and our vision of delivering to consumers and merchants a secure, converged payments experience in-store, online or on a mobile device," he noted in a statement.
The trial builds on pilot work in which a pump course using DAFNE principles was developed.
The trial builds on preliminary evidence from the Scottish CHEST Trial, which showed promising results for altering symptom appraisal and help-seeking behaviour.
This trial builds on two previous studies that indicated restructuring FBT with parents and adolescents attending separate sessions may be an efficacious alternative treatment for some families.
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CEO of Professional Science Editing for Scientists @ prosciediting.com