Sentence examples for trial as a proof of from inspiring English sources

Future studies, especially that target antifibrotic mechanisms, may utilize the MRE protocol used in this trial as a proof of concept for noninvasive and quantitative assessment of treatment response.

Of these, the use of plerixafor is currently the most promising for further investigations in human clinical trials as a proof of principle, as this drug is already approved for clinical use.

Therefore, the GIPS-III trial may be regarded as a proof-of-principle trial focused on the cardioprotective effects of metformin.

Therefore, the trial could be described as a "proof-of-principle" pilot study.

In this work, and as judiciously stated by the authors, the trial was only designed as a proof-of-concept and dose-finding study.

The trial is designed as a proof of principle, to establish whether the robot can do what an eye surgeon does, but with greater accuracy.

The PREVENT trial was designed as a "proof of concept" to demonstrate that it is possible, in the clinical setting (as reflected by our use of an intention-to-treat analysis), to reduce bone resorption sufficiently to be clinically relevant.

Monotherapy activity was observed in early trials of these rapalogs, serving as a proof-of-concept for targeting the PI3K-AKT-mTOR pathway [59].

We applied yeast two-hybrid and in vitro binding assays as a proof-of-concept trial for analysis of the newly identified proteins for binding to Hsp90.

The reasons for discontinuation are listed in figure 2. As a proof-of-concept trial, we primarily needed to answer whether the interventions were effective for those patients who adhered to the assigned treatment, which was the per-protocol analysis.

The intravenous randomised controlled trial of lasmiditan [15] should be considered as a proof-of-concept study validating the principle of 5-HT1F receptor agonism in the acute treatment of migraine.