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One limitation of this randomised phase II trial arises from the fact that an analysis of patterns of treatment failure (local vs distant) was not included.
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These points argue against selection bias in the AXIS trial arising from preferential recruitment of more affluent patients on the grounds of lower comorbidity.
The questions being addressed in the trial arose from analyses of the predicted impact of mass treatment based on mathematical models of the transmission dynamics and control of STHs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com